Publications


For full List of publications click here.

2022

Lou K, Wassarman DR, Yang T, Paung Y, Zhang Z, O'Loughlin TA, Moore MK, Egan RK, Greninger P, Benes CH, Seeliger MA, Taunton J, Gilbert LA, Shokat KM.Science. 2022 Dec 9;378(6624):1097-1104. doi: 10.1126/science.abl5829. Epub (2022 ) (PMID: 36480603)

2021

Nunez, J. et al. Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing . Cell. 184(9):2503-2519. (2021) (PMID: 33838111)

2019

Lou, K. et al. KRAS G12C inhibition produces a driver-limited state revealing collateral dependencies. Sci Signal.12(583) (2019) (PMID: 31138768)

2018

Horlbeck, M. A. et al. Mapping the Genetic Landscape of Human Cells. Cell 174, 953–967.e22 (2018). (PMID: 30033366)

2017

Liu, S. J. et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science 355, 7111 (2017). (PMID: 27980086)

Jost, M. et al. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Mol. Cell 68, 210–223.e6 (2017). (PMID: 28985505)

2016

Adamson, B. et al. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell 167, 1867–1882.e21 (2016). (PMID: 27984733)

Horlbeck, M. A. et al. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife 5, (2016). (PMID: 27661255)

 2015

Zalatan, J. G. et al. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell 160, 339–50 (2015). (PMID: 25533786)

2014

Tanenbaum, M. E., Gilbert, L. A., Qi, L. S., Weissman, J. S. & Vale, R. D. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell 159, 635–46 (2014). (PMID: 25307933)

 

Gilbert, L. A. et al. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell 159, 647–61 (2014). (PMID: 25307932)

2013

Chen, B. et al. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell 155, 1479–91 (2013). (PMID: 24360272)

Qi, L. S. et al. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152, 1173–83 (2013). (PMID: 23452860)

Gilbert, L. A. et al. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell 154, 442–51 (2013). (PMID: 23849981)